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History of Epidemiology: Patient Zero and Typhoid Mary

ResearchBlogging.orgBetter Know An Epidemiologist/History of Epidemiology is an ongoing feature where Mr Epidemiology pays tribute to people and studies that have set the stage for his generation of epidemiologists. All of the articles are listed here.

Gaetan Dugas, Air Canada flight attendant and one of the first diagnosed cases of HIV

EDIT 10/01/12: I had indicated (incorrectly) that Typhoid Fever was a viral disease. It is in fact due to a bacterium instead. Thanks to Mike the Mad Biologist for pointing that out!

EDIT 10/01/12: As Brett Keller points out in the comments, Gaetan Dugas was not Patient Zero for HIV. While he contributed to the spread of the virus, he wasn’t the first known case of it, and so the label of Patient Zero is unfairly applied to him.

Patient Zero is a common infectious disease epidemiology term. It refers to the first known case of the disease of interest, and is useful when tracking disease outbreaks. Knowing where the disease starts allows us to track not only the spread of the disease, but also how it spreads – through water, air, person-to-person contact etc.

I heard an absolutely phenomenal podcast through WNYC’s RadioLab podcast about Patient Zero, and that formed the inspiration for this post. I highly recommend listening to it when you have a chance – either through iTunes, on their website. They cover several different “Patient Zero’s,” including Typhoid Mary and Gaetan Dugas (pictured above).

Today, I’ll be talking about Typhoid Mary. To listen exclusively to the Typhoid Mary segment of the RadioLab podcast, click here.

Click the image to go to the RadioLab podcast about Patient Zero.

Continue reading “History of Epidemiology: Patient Zero and Typhoid Mary”

History of Epidemiology: Jonas Salk and The Eradication of Polio

Better Know An Epidemiologist/History of Epidemiology is an ongoing feature where Mr Epidemiology pays tribute to people and studies who have set the stage for his generation of epidemiologists. All of the articles are listed here.

Poliomyelitis is an infectious viral disease. It enters through the mouth and is usually spread by contaminated drinking water or food. The virus passes through the stomach and then replicates in the lining of the intestines. Most healthy people infected with virus experience little more than mild fever or diarrhea. However, some people develop paralysis, and some die as a result.

Franklin Delano Roosevelt, 32nd President of the United States of America, suffered from Polio

In 1952, approximately 58,000 new cases of Poliomyelitis occurred in the United States. In 1953, approximately 35,000 new cases were reported. This was up from an annual average of 20,000 cases. The 1952 infections left 3,145 people dead and 21,269 with mild to disabling paralysis.

Even before the 1952 and 1953 outbreaks, labs had been worked diligently to find a cure for Polio. Relief finally came when Jonas Salk developed a vaccine.

More after the jump.

Continue reading “History of Epidemiology: Jonas Salk and The Eradication of Polio”

Better Know An Epidemiologist: Alexander Langmuir

Better Know An Epidemiologist/History of Epidemiology is an ongoing feature where Mr Epidemiology pays tribute to people and studies who have set the stage for his generation of epidemiologists. All of the articles are listed here.

Epidemiology is a relatively new field. While John Snow made his breakthrough in the 1850s, even as recently as World War 2, there was no central epidemiology agency. However, with the start of the Korean War, the threat of biological warfare loomed. As a result, the government recognized the need for an organization who would track and monitor disease outbreaks.

Enter Alexander Langmuir.

Alexander Langmuir, founder of the Epidemic Intelligence Service

Continue reading “Better Know An Epidemiologist: Alexander Langmuir”

Better Know An Epidemiologist: John Snow

Better Know An Epidemiologist/History of Epidemiology is an ongoing feature where Mr Epidemiology pays tribute to people and studies who have set the stage for his generation of epidemiologists. All of the articles are listed here.

Edit 11/02/11: I added in a link to a Google Map of the cholera outbreak

There have been many breakthroughs made off the blood and sweat of Epidemiologists. They have been at the forefront of eradicating polio, smallpox, reducing deaths from cholera and even detecting thalidomide as a teratogen.

But we will start at the beginning with the first Epidemiologist, John Snow.

More after the jump.

Continue reading “Better Know An Epidemiologist: John Snow”

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